1. Non-healing infected deep ulcerations (reaching tendons or bone) of the lower extremity in diabetic adults unresponsive to at least 1 month of meticulous wound care (including aggressive debridement, maximal antibiotic therapy, tight glycemic control, and appropriate treatment of arterial insufficiency, including revascularization if necessary). HBOT is not considered medically necessary for superficial lesions.
2. Acute carbon monoxide poisoning
3. Decompression illness (“the bends”)
4. Acute air or gas embolism
5. Gas gangrene (Clostridial myositis and myonecrosis)
6. Cyanide poisoning (with co-existing carbon monoxide poisoning)
7. Acute traumatic peripheral ischemia (including crush injuries and suturing of severed limbs) when loss of function, limb, or life is threatened and HBOT is used in combination with standard therapy
8. Acute peripheral arterial insufficiency (i.e., compartment syndrome)
9. Progressive necrotizing soft tissue infections, including mixed aerobic and anaerobic infections (necrotizing fasciitis, Meleney’s ulcer)
10. Chronic refractory osteomyelitis, unresponsive to conventional medical and surgical management
11. Compromised skin grafts and flaps
12. Radiation necrosis (osteoradionecrosis, myoradionecrosis, brain radionecrosis, and other soft tissue radiation necrosis)
13. Radiation proctitis
14. Exceptional blood loss anemia only when there is overwhelming blood loss and transfusion is impossible because there is no suitable blood available, or religion does not permit transfusions
15. Pneumatosis cystoides intestinalis
16. Prophylactic pre- and post-treatment for members undergoing dental surgery of a radiated jaw
17. Acute cerebral edema
18. Idiopathic sudden deafness, acoustic trauma or noise-induced hearing loss, when HBOT is initiated within 3 months after onset.