HBOT can help to heal bone disorders by stimulating both the osteoclasts and the osteoblasts. This helps and leads to the re-absorption of dead bone and the creation of new bone. In addition, HBOT stimulates the production of new blood vessels, so that the growing bone receives a steady supply of nutrients, including oxygen. The increased blood vessel network that HBOT yields does two other things: it helps support the function of the osteoclasts, and brings infection fighting white blood cells to the area.

Osteomyelitis is a bacterial infection that usually involves both the outer layers of the bone and the inner bone marrow. Staphylococci, is a common form of bacteria that can cause infections ranging from pimples to meningitis. Staphylococci are an anaerobic (oxygen hating) bacteria, making HBOT ideal for controlling its spread.

* Chronic osteomyelitis may follow an acute form or may develop over time; this is also when the acute form is not completely cured by treatment.
* Long –term Osteomyelitis which in some cases continues for years.
* Refractory osteomyelitis is a term referring to the condition of bone infection that did not respond to either surgical or antibiotic therapy

Part of the difficultly in treating osteomyelitis lies in the fact that it causes a lack of oxygen in the tissues. HBOT, by providing forced oxygenation, helps fight this disorder along with antibiotic therapy and or surgical intervention. Hyperbaric Oxygen Therapy helps preserve healthy bone, restore, and help build new bone and helps with the immune system. In some cases, in both bones and wounds, HBOT draws a clear line by which the surgeon can aid in the removal of dead or diseased bones. These types of infections can occur sometimes in the extraction of a tooth.

A good three-part treatment for bone infections includes the use of antibiotics, surgery to remove the dead bone, and HBOT as a supporting or adjunct treatment. There are some surgeons who are using HBOT before and after surgery.