Hyperbaric Oxygen Therapy (HBOT) is an important adjunct in the treatment of non-healing wounds.  An established technology, Hyperbaric Oxygen Therapy has been shown to help in treating:

* Refractory Osteomyelitis
* Crush Injuries
* Radiation Tissue Damage
* Acute Traumatic Ischemia
* Comprised Skin Grafts, Flaps and Replants
* Necrotizing Soft Tissue Infections
* Diabetic Ulcer of the Lower Extremity

Hyperbaric Oxygen Therapy involves the systemic delivery of oxygen to patients placed in a chamber at two to three times atmospheric pressure while breathing 100 percent oxygen for periods of time between 90 to 120 minutes.

The effects of increased oxygen tension include:

* Vasoconstriction and the reduction of edema in the area of trauma for crush injuries. Tissue oxygen levels may be 10 to 20 times that achieved by normobaric oxygen breathing.
* Increase in oxygen diffusion distance from functioning capillaries in the hypoperfused wound. Oxygen is necessary for the functioning of fibroblasts, osteoclasts, and granulocytes in wound healing. Also, oxygen is necessary for healing skin grafts, selected problem wounds and compromised flaps.
* Stimulation of neovascularization in ischemic tissues (radiation necrosis, small vessel disease in diabetes, flap, and graft failure).
* Support of leukocytic oxidative bacterial kills as an adjunct to antibiotics and good wound care.